CD117 is a member of the tyrosine kinase receptor family and is expressed by subsets of hematopoietic progenitor cells and mast cells. This proto-oncogene binds to stem cell factor to form a dimer. This interaction promotes proliferation and differentiation of hematopoietic progenitor cells, and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells.
710523 detects c-Kit/CD117 in Human samples. 710523 has been successfully used in WB procedures. The immunogen for 710523 is peptide corresponding to amino acids 246-261 of human CD117 (c-kit).
Applications:
Western Blotting
CD117; Mast/stem cell growth factor receptor Kit; p145 c-kit; PBT; Piebald trait protein; Proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; SCFR; soluble KIT variant 1; Tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Cat # 15337354
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Cat # 15367134
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Cat # 16888564
150 µL
Cat # 16898564
20 µL
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